172 Life Science Properties for Lease in Massachusetts, USA

Somerville Office for Lease - Somerville/Everett

74M is a breakthrough life science development in Somerville, Massachusetts. Currently, under construction, the 15-story purpose-built lab office building will contain 465,000 square feet of space. Through incorporating cutting-edge design, services, and amenities, 74M is the next life science development centered in the vibrant Somerville innovation community. Experience state-of-the-art labs that support mission-critical research and development. 74M is LEED Platinum, WELL Platinum, and WiredScore Platinum certified – meeting exceptional standards for infrastructure, energy efficiency, and tenant well-being. The building’s focus isn’t just on scientific advancements but also on the scientists who discover them. On-site amenities include an expansive rooftop lounge and event space featuring expansive skyline views, a well-being center featuring fitness and spa-style facilities, an expansive outdoor terrace, and more. 74M offers easy accessibility and unparalleled visibility directly adjacent to I-93 and a short walk to the MBTA Orange Line station. The development creates connectivity between the highly amenitized Assembly Square and the authentic cafes and restaurants of East Somerville. Enjoy unencumbered views of Boston, Cambridge, and the Mystic River throughout the workday and benefit from proximity to a highly educated and talented workforce. 74M is an ideal destination for today’s innovators within a 10-minute drive of Kendall Square and Logan International Airport.

Date on Market:

2024-03-28

Westborough Office, Flex for Lease - The Boroughs

One Research Drive is a four-story, 283,797-square-foot Class A office building in the heart of the Westborough Business Park. It offers unmatched accessibility, modern amenities, and professional management. Visible from Route 9 and minutes from Interstate 495 and the Massachusetts Turnpike, the property's prime location ensures frictionless connectivity to Boston and surrounding areas. Designed to meet the evolving needs of today's workforce, One Research Drive has undergone significant capital improvements, including a fully renovated lobby, LED lighting upgrades, glass railing systems, modernized common areas, enhanced restrooms, and updated HVAC systems. The property features best-in-class amenities, such as a 140-seat auditorium, an executive boardroom with catering space, a full-service cafeteria with an outdoor patio, high-speed wireless internet in common areas, and a well-equipped fitness center with locker rooms and showers. Additional conveniences include an on-site ATM, abundant surface parking, and an elevated walkway that leads to the third-floor lobby entrance. One Research Drive tenants benefit from convenient public transit access, with the WRTA shuttle providing direct service from the MBTA Westborough Commuter Rail Station. As a recipient of the Energy Star label since 2007, One Research Drive remains committed to sustainability, with plans for EV chargers and expanded renewable energy initiatives. Professionally managed by Ferris Development Group, this premier office destination offers a dynamic, well-connected, and energy-efficient workplace designed for success.

Date on Market:

2025-09-30

Salem Multiple Space Uses for Lease - Peabody/Salem

Situated on a sprawling 30-acre oceanfront property across five distinct buildings, Shetland Park is a prestigious 1.5 million-square-foot business center. Versatile office, flex, and industrial space is currently available for lease in various ranges, from private suites to large blocks. Tenants have the exciting opportunity to craft modern, unique workspaces with mesmerizing views of the harbor in flexible configurations. Key property features include surface and covered parking, 24-hour access, high-speed internet, upgraded common areas, and on-site security. Flex users can access tailboard loading and 14- to 23-foot ceiling heights. This dynamic campus also features health and wellness professionals, a full-service salon, a caterer, a gym, a cross-fit facility, an event space, and a childcare center. For businesses seeking a prominent setting with picturesque views, Shetland Park presents the ideal opportunity. Its prime location near Salem's flourishing downtown amenities enhances the overall appeal. Space is immediately available for tenant occupancy and offered at competitive lease rates alongside attractive tenant improvement packages. Shetland Park's Salem Harbor location adds to the allure of the property, fostering a unique business/lifestyle atmosphere with easy access to restaurants and shops. Moreover, tenants enjoy swift connectivity to Route 128 and a mere 35-minute drive south to Downtown Boston. Mass transit users find that traveling to and from the property is a breeze as the Salem MBTA station, with commuter rail and bus access, is within convenient walking distance. The campus's prestige, attractive rates, and excellent accessibility make Shetland Park a highly desirable business center within vibrant surroundings. This property is a must-see, with showings available by appointment only.

Date on Market:

2025-03-24

Acton Flex, Industrial for Lease - Concord/Maynard

100 Discovery Way is a premier, multi-tenant property in Acton, Massachusetts that can accommodate industrial, manufacturing, flex, and office users . The 100,000-square-foot building offers exceptional Route 2 visibility within minutes of Route 128 and Interstate 495. This high-profile facility is situated on 14.48 pristine acres and comprises best-in-class office, manufacturing, and flex space. Professional landscaping, abundant parking, and a double-height atrium lobby with a reception and seating area make a strong impression on tenants and visitors. The 100% air-conditioned building features an employee breakroom and an on-site fitness center. Plus, utilize an expansive warehouse with two loading docks, heavy power, and an 18-foot clear height for manufacturing and distribution. Acton presents residents and businesses with a charming suburban setting, encompassing numerous public parks and gorgeous scenery. 100 Discovery Way sits 30 miles northwest of Downtown Boston, near the Great Hill Recreation Area. Numerous retailers, cafes and restaurants are reachable via the Massachusetts Avenue and Great Road commercial corridors.

Date on Market:

2023-06-16

Lawrence Multiple Space Uses for Lease - Lawrence/Andover

The Riverwalk Innovation District in Lawrence, Massachusetts, offers a rare opportunity to lease fully renovated office, flex, medical, manufacturing, and retail space. As Merrimack Valley's premier mixed-use campus, the historic 3.5 million-square-foot complex blends 19th-century mill architecture, including exposed wood beams, exposed brick details, and soaring interiors, with modern finishes, such as upgraded lighting, HVAC, restrooms, and break areas. The Pavilion provides ready-to-go and build-to-suit space options for businesses of all sizes, from boutique offices to large institutional tenants, with flexible lease terms available. Located directly off Interstate 495 and adjacent to the Lawrence MBTA Commuter Rail, The Pavilion offers exceptional accessibility and a dynamic, amenity-rich environment. Tenants enjoy a mix of on-site dining, retail, banking, fitness facilities, a full athletic field, child care, waterfront restaurants with patio seating, and a underground parking garage with over 1,250 spaces. Outdoor green space, beautiful river views, and a true live-work-play atmosphere create a standout environment for growth and innovation. Join leading companies and prominent retailers at The Pavilion and capitalize on a premier campus that combines historic character, modern amenities, and unmatched convenience.

Date on Market:

2025-08-04

Worcester Multiple Space Uses for Lease - Worcester Metro

The Landing at Worcester Mills, located at 60 Fremont Street, introduces a rare mixed-use leasing opportunity within a newly revitalized asset offering build-to-suit flex, warehouse, storage, office, and creative loft studios designed for maximum flexibility. Under new ownership and management, the property benefits from a well-capitalized team prepared to retrofit and build space to meet a wide range of user needs, including office, lab, manufacturing, logistics, and last-mile distribution. The building features up to 18-foot warehouse ceiling heights, a substantial first-floor warehouse footprint ideal for an anchor tenant with loading access, a second floor suited for office, workshop, or light industrial use, and a third floor fully dedicated to flex space with high ceilings and oversized windows that deliver abundant natural light. Additional basement space, ample onsite parking, resurfaced lots, two freight elevators, and robust power support operational efficiency. The Landing at Worcester Mills offers functional, flexible spaces ranging from 3,000 to over 17,000 square feet, accommodating a wide variety of occupants. Ideally situated in central Massachusetts, 60 Fremont Street delivers exceptional connectivity and distribution access throughout New England. The site is minutes from Interstates 290, 90 (Mass Pike), 495, and Routes 20, 12, and 9, placing regional markets within reach. Downtown Worcester, Polar Park, and Union Station are approximately a 10-minute drive, providing access to Amtrak, MBTA Commuter Rail service, and regional bus lines. Freight and air logistics are supported by proximity to the CSX Worcester Rail Yard and Worcester Regional Airport, both within a short drive, with Boston Logan International Airport and the Port of Boston accessible within an hour. The surrounding area offers strong day-to-day conveniences, including national retailers such as Shaw’s, CVS, Marshalls, and Planet Fitness, while downtown continues to expand with new residential development and amenities. Located within a growing and business-friendly market, The Landing at Worcester Mills benefits from Worcester’s expanding population and a labor force exceeding 203,000 within a 10-mile radius. The city’s strong academic presence, anchored by institutions such as Worcester Polytechnic Institute, College of the Holy Cross, Worcester State University, and Quinsigamond Community College, supports a deep and educated talent pipeline for healthcare, biotech, technology, and advanced manufacturing users. Worcester’s position as a gateway city to the Northeast enables faster deliveries, broader reach, and lower freight and logistics costs, reinforced by significant transportation infrastructure. Local and state programs further enhance the opportunity through potential tax incentives for qualifying job-creating investments. The Landing at Worcester Mills is ideal for companies seeking space that can evolve.

Date on Market:

2025-09-26

Hopkinton Office for Lease - Hopkinton/Holliston

35 Parkwood Drive, located within the Hopkinton Corporate Center in Hopkinton, Massachusetts, presents an exceptional opportunity to lease Class A office space. Formerly the EMC World Headquarters, the best-in-class two-story multi-tenant building underwent a comprehensive renovation in 2018 and now features a modern main lobby, large conference rooms, outdoor patio space, updated common areas, four passenger elevators, a fitness center with showers, and on-site service kiosks. Available suites range from approximately 4,155 to 12,150 square feet on the first and second floors, with flexible configurations and negotiable lease terms to suit various professional office and R&D users. Month-to-month coworking opportunities are also available through Regus. Tenants benefit from heavy power infrastructure, telecom/data wiring throughout the building, and abundant parking. Just a half-mile off Interstate 495 at Exit 54, one exit south of the Mass Pike, 35 Parkwood Drive offers excellent regional access about 40 minutes southwest of Boston. Nearby amenities include Starbucks, Dunkin', 110 Grill, Cumberland Farms, and The Spoon café. Owned and managed by the same experienced team, the property delivers reliability, responsiveness, and a high-quality work environment.

Date on Market:

2025-05-22

Randolph Office/Medical for Lease - Route 24

50 Thomas Patten Drive is a professional office and lab building in Randolph, Massachusetts. The two-story building contains nearly 30,000 square feet and was completely renovated in 2019. Recent upgrades to the landscaping, façade, and bathrooms, along with ample surface parking, impress both employees and clients visiting this exceptionally maintained property. Up to 15,000 square feet of first-floor, mixed-use office and lab space is immediately available for occupancy. This space is in move-in-ready condition or can be customized to exact specifications. Benefit from 36 large cubicles that are pre-wired for networking and professionally cleaned, 13 spacious perimeter offices, and a generous conference room. The first floor also boasts lab space with a fire suppression system and access to a loading dock. The all-inclusive rent includes heat, hot water, electricity, taxes, and no surprises. 50 Thomas Patten Drive sits 20 miles south of Boston. Commuters can reach Route 24 within a three-minute drive and benefit from convenient access to Route 3 and Interstates 95 and 93. Surrounding amenities, like Dunkin', Outback Steakhouse, a United States Postal Service office, Holiday Inn Express, Showcase Cinema de Lux, and the Randolph Dog Park are only a short drive away.

Property Type:

Office

Date on Market:

2019-01-09

Canton Office, Industrial for Lease - Route 1 South

Canton Corporate Place at 15-45 Dan Road is a prominent two-building office, research and development (R&D), and industrial complex in Canton, Massachusetts. The campus consists of 45 Dan Road, a three-story building connected to 15 Dan Road, a single-story office and industrial facility. There are renovated common and lobby areas, a full-service café, conference and fitness centers, locker rooms with showers, and an outdoor seating area. Various suite sizes are immediately available for occupancy among the building's diverse tenant roster, including The Home Depot's New England regional offices, Bayada Home Health, Expert Roofing & Siding Construction, and more. Lease terms are negotiable, with some space in move-in-ready condition and efficient floor plates to take business operations to the next level. Canton Corporate Place sits just off Route 138, which features an array of dining, retail, and convenience options. Access to three major highways, including Route 24 and Interstates 95 and 93, is within 3 miles of the property. Blue Hills Ski Area, the Norwood Memorial Airport, and other surrounding points of interest are only moments away from the tranquil property.

Date on Market:

2025-11-06

Woburn Office, Flex for Lease - Burlington/Woburn

A recently upgraded office and R&D park less than a mile from the intersection of I-93 and I-95/Route 128 and minutes from the Anderson Regional Transportation Center (MBTA), Gill Street is a compelling option for employers seeking a central location, high quality, great value, and Cummings Properties’ extensive in-house capabilities. The campus offers first class office space, ample free parking, and numerous amenities within minutes of the building. Nearby dining options include Jake n Joes Sports Grille, 99 Restaurants, and the Chateau Restaurant Woburn.

Date on Market:

2025-08-19

Malden Office for Lease - Medford/Malden

Discover Exchange 200, offering state-of-the-art lab, GMPc, R&D, and creative office space with robust infrastructure, steps from transit. Exchange 200 is complete and ready to accommodate the requirements of today’s growing life sciences and technology tenants. The development site is situated at an outstanding transit-oriented location directly across from the Malden Center T-Station, with direct access to the MBTA Orange Line, Commuter Rail, bus connections, and bike paths. Travel to Downtown Boston in just 12 minutes, only one stop from North Station on the Commuter Rail or five stops on the Orange Line. Exchange 200 has undergone a transformative redevelopment that firmly establishes the 300,000 SF building as the next destination for Greater Boston’s cutting edge companies. Featuring state-of-the-art new building systems, a two-story lobby, fitness center, bike storage and a host of other, first-class amenities that appeal to today’s life sciences and creative office workforce, the reimagined space offers a vibrant work environment, bolstered by activated ground-floor retail with outdoor seating. Anchored by the renowned coffee house, Starbucks, tenants can enjoy this well-known laid-back atmosphere as a place to meet up with colleagues, grab a bite to eat, or relax without ever having to leave the building. Two full-service restaurants, Evviva Trattoria and 110 Grill, offer an extensive variety of food options along with vibrant outdoor patio spaces. Malden is a diverse community, emerging as a new residential and commercial hotspot with over 1,000 new luxury residential units. Just five miles from Boston, enjoy the charm of a small town and the amenities of one of America's largest cities.

Date on Market:

2024-06-11

Medford Office, Flex for Lease - Medford/Malden

This unique property, located off Boston Avenue, offers easy access to a diverse vibrant community known for its restaurants, shops, urban gardens, cutting-edge research and academic institutions, and numerous public transportation options. The building offers superior office and lab facilities with a unique, urban feel. Affordable offices while being close to both the suburbs and the city. Medford is home to Tufts University, and several other major academic institutions, Harvard and MIT are in proximity. Medford and Somerville are easily reached by public transportation and are just minutes from I-93.

Date on Market:

2025-04-07

Waltham Flex for Lease

This impressive flex property offers a versatile space ideal for a wide range of business needs. Built in 1975, the building encompasses 207,600 square feet and is situated on a generous 7.28-acre lot. With a clear height of 20 feet and 25-foot by 25-foot column spacing, the space is well-suited for both office and industrial applications. The property includes six drive-in bays, providing easy access for loading and unloading, and features ample parking with 345 standard spaces, ensuring convenience for employees and visitors alike. Explore the potential of this flexible space to elevate your business operations!

Date on Market:

2025-08-13

Bolton Office for Lease - Outlying Worcester

KW Commercial and Northeast Solutions at KW Commercial proudly present Class A office space available within the Bolton Square Offices. The office/ flex building is situated on 6.5 beautifully landscaped acres at 580 Main Street in Bolton, Massachusetts. Bolton Square Offices is a three-story building offering flexible space characterized by a brick façade, expansive window lines, and views of wooded areas and ponds. This accommodating office property boasts excellent amenities and tenant common areas, fostering a fresh and contemporary environment for businesses and their employees. Among the new amenities is a modern, on-site gym exclusively for tenants, supporting health and wellness in the workplace. Spacious exterior green spaces offer attractive options for outdoor gatherings, relaxation, and events. The building features a variety of office suites on the first and second floors that can be combined or reconfigured to suit individual business requirements. The lower level offers additional flex or lab space. Loading docks and elevators facilitate business operations throughout the property. With its beautifully landscaped grounds, newly enhanced amenities, and adaptable layout, 580 Main Street delivers a scenic, accessible, and contemporary workspace solution in central Massachusetts, just 15 miles from Interstate 90/ Massachusetts Turnpike. Plus, tenants enjoy the built-in convenience of proximity to numerous restaurants, daycare centers, and hotels within a 5-mile radius. Inquire today for more information about Bolton Square Offices, which offer excellent potential for professional users and accommodate a wide range of business needs.

Date on Market:

2025-10-30

Charlestown Office, Industrial for Lease - Charlestown/East Boston

500 Rutherford Avenue, situated within the Hood Park 20-acre mixed-use urban campus, is a beautifully renovated three-story facility in Charlestown, Massachusetts. Presenting approximately 125,000 square feet of new construction, the 300,000-square-foot building has been re-adapted to serve a diverse user base. Tenants experience a dynamic setting with abundant on-site parking, efficient floor plans, a private lounge area, and high-visibility signage potential. Current availability includes first-generation research and development (R&D), lab, and manufacturing space. Tenants benefit from ample 1,200-amp, 480-volt power and a fully furnished leasing opportunity with office and lab equipment included. There’s also an additional 6,000 square feet of open warehouse/industrial space with a 16-foot clear height that can easily be brought up to code for a variety of uses. Plus, the potential to tie into RODI (Reverse Osmosis Deionization) and pH neutralization systems are available. 500 Rutherford Avenue offers a vibrant and well-connected setting for modern businesses. Tenants enjoy convenient Hood Park amenities like Tradesman Coffee Shop & Pizza Bar, Urban Wild live music venue, Element Salon and Spa, and Hotbox by The Handle Bar fitness studio. The property offers direct Interstate 93 connectivity for swift travel to Downtown Boston and is close to the North Station and Assembly Row commercial hubs. For added convenience, tenants benefit from electric vehicle charging stations and shuttle service to nearby MBTA stations. Combining cutting-edge facilities with desirable amenities, 500 Rutherford Avenue offers an ideal location for businesses seeking a seamless work-life balance.

Date on Market:

2024-11-12

Cambridge Office for Lease - Mid-Cambridge/Harvard Sq

Choose a prime location in the heart of Cambridge, Massachusetts, with the contemporary office spaces available for lease at 1035 Cambridge Street. This versatile office building offers a unique blend of modern amenities and historic charm, making it an ideal location for businesses of all types. New tenants will be able to join a performing roster of technology, biotech, healthcare, real estate, architecture, coworking, and not-for-profit companies. The available suites at 1035 Cambridge Street come in a wide variety of sizes between 1,518 and 7,136 square feet, with flexible layouts and contemporary features. Most of the units are equipped with private offices, conference rooms, break areas, and open workspaces. Suites come in a variety of finishes, with carpeted or wood flooring, large windows, and attractive built-ins. Tenants at the property enjoy access to a shared conference center facility, common area bathrooms with showers, and abundant on-site parking for 150 vehicles. 1035 Cambridge Street was originally built in 1930 and extensively renovated over the years, spanning a total of 99,500 square feet across three floors. The building’s spacious lobby enters a dramatic two-story atrium with an impressive, oversized skylight and brick and beam finishes, creating a welcoming atmosphere for clients and employees. Tenants have 24/7 access to the property, with card readers and video cameras for security. Centrally located at the heart of Cambridge, 1035 Cambridge Street situates tenants within an established hub near a wealth of quality urban amenities. The location is just a third of a mile from Union Square and Inman Square, both major commercial centers of the region with excellent restaurants and specialty stores. Offering convenient accessibility for commuters, the property sits just a short distance from major highways, including Highway 28 and Interstate 93. Providing additional access options, the site is a short walk from the Union Station Green Line stop, as well as several bus stops, and there are Zipcars and Hubway bikes on-site. Situated approximately 1 mile from both Harvard University and the Massachusetts Institute of Technology, businesses at 1035 Cambridge Street have access to one of the nation’s strongest talent pipelines, which can fuel future growth and expansion. When looking within just 1 mile of the property, tenants can tap into a sizable workforce of more than 68,000, with over 70% of locals carrying a bachelor’s degree or higher. Unlock premier office space at 1035 Cambridge Street, combining modern amenities, flexible layouts, and an unbeatable Cambridge location, with access to top talent, transportation, and vibrant commercial centers. Reach out to the Lee & Associates team today to schedule a tour and find the perfect space.

Date on Market:

2025-11-28

Watertown Office for Lease

Conveniently located in prime Watertown, MA, 66 Galen St is a newly built lab building offering 224,106 RSF with an expansion opportunity of up to 224,000 RSF in Phase II of the campus. Situated on a 5-acre campus plan, including 1 acre of lush green space, this building boasts LEED Gold Certification and approximately 25,000 SF of solar panels, aligning with your sustainability goals. Amenities abound, with a fitness center featuring locker rooms, an outdoor roof deck, and close proximity to biking and running trails.

Date on Market:

2024-03-21

Beverly Office, Flex for Lease - Danvers/Beverly

Cummings Center is the North Shore's premier business address, a true mixed-use development that blends commercial, retail, and residential in one place. The round-the-clock office, retail, and restaurant energy enhances the Cummings community and the City of Beverly. 100 Cummings Center is the core building on campus, with five-floors of various sized suites, many entrances, elevators, loading docks, covered bridges to parking garages, and restaurants. This building boasts office, lab, flex, R&D, and retail commercial offerings. Resident clients enjoy an array of on-site amenities including restaurants, a gym, a U.S. Post Office, full-service bank, child and adult day cares, medical, dental, and other specialized health services, salons, C.P.A's, insurance agents, mortgage brokers, computer sales and services, and a choice of internet and telephone providers. Originally constructed in 1906 as the United Shoe Machinery Corporation, Cummings Properties purchased and re-built this historic landmark in 1996.

Date on Market:

2025-09-23

Woburn Office, Flex for Lease - Burlington/Woburn

Cummings’ flagship property at TradeCenter 128 offers more than 500,000 square feet of unparalleled office space. Directly fronting I-95 in Woburn and less than one mile from I-93, this superb site is broadside to one of the most traveled Interstate highway segments in New England. TradeCenter 128 clients enjoy the finest quality corporate lifestyle with the amenities of a central business district, including free garage parking, a first-class restaurant, a scenic outdoor park, and easy access to a wide variety of dining and retail options.

Date on Market:

2025-01-27

Wilmington Flex for Lease - Wilmington/Reading

Date on Market:

2026-01-06

Woburn Office for Lease - Burlington/Woburn

Date on Market:

2025-11-06

Billerica Retail for Lease - Lowell/Chelmsford

Date on Market:

2025-09-04

Cambridge Flex for Lease - E Cambridge/Kendall Sq

Brokers Welcome! A clean and well-maintained, privately owned building in the vibrant East Cambridge neighborhood with close proximity to public transportation, Kendall Square and Route 93. Lechmere station is just 7 minutes away on foot, or take the on-site #69 MBTA bus toward Lechmere or Harvard Squares. Great restaurants, coffee shops, markets and grocery stores all within walking distance. Currently 1 Unit Available on November 1, 2025 which includes 4033 Suite B1 and 689 SF Suite 102 ($22.50 NNN + $7.50): Cambridge is finally affordable again! A rare, flexible, low-cost, grandfathered distribution/tech/light manufacturing/contractor/storage/R&D/repair/lab space with plenty of office/desk & conference space in the heart of a dynamic East Cambridge neighborhood. 800 amp, 3-phase 208V electrical service. A dedicated, 6500 lb material lift with 4’ x 8’ car, features a straight shot from the parking/loading area through the 689 sf first floor office space, and down to the lower level’s 4033 sf flex space. Includes 2 lab sinks, kitchen/break room, 3 different HVAC systems with app control. Private restroom with private shower included. First floor features a dedicated office and open conference room space with giant, south-facing windows. Lower level features new, epoxy flooring throughout. Wired networking capable of 10GB and rack space available. Up to 6 parking spaces are available for an additional fee. 24 hour, swipe/prox card secure access. Starter workstations and tables shown in photos may be included as desired. The combined 4722 sf space comes as a single, indivisible unit.

Property Type:

Office

Date on Market:

2025-07-10

Canton Flex, Industrial for Lease - Route 1 South

Beautiful hardwood floors and lots of natural light.

Date on Market:

2025-04-28