447 Life Science Properties for Lease in California, USA

San Diego Flex for Lease - Mira Mesa/Miramar

Spec Biotech / Life Science conversion delivering June 2024. Spec lab being built per the plans. • Brand New Spec ~35K SF Life Science Conversion • Base Building Improvements to accommodate lab • Exterior Façade Renovation to include a new glass curtain wall on the front of the building • New 2-Story Lobby • Refreshed Landscaping • Large terrace on the 2nd floor • Strong Ownership Team with Proven Life Science Track Record LAB SPECS 10ft dropped ceiling in lab area - (clear to deck is 23ft) 9ft dropped ceiling in office areas Benching and casework included in spec build in the majority of the lab area Labs to include three (3) new VAVs with 100% outside air and airflow rate of 9 ACH per hour Two (2) new heating hot water boilers will include N+1 redundancy on the boilers as well as the pumps House Vacuum and Compressed Air included in spec Fume Hood - One (1), 6-ft hood and capacity for 3 additional Power - 2000A 480/277V (3000A of 208/120V) Back-up Generator - 150kw

Date on Market:

2021-12-10

Monterey Office for Lease - North Monterey County

Mahoney and Associates is pleased to present for sublease three turn-key office spaces in Monterey. These prime, furnished spaces are located off of Highway 68/218 between Monterey and Salinas. The building has a complete Marriott run cafeteria, ample parking, men's and women's locker rooms, and full-time security at the main entrance. Suite 106 is ±20,270 SF, Suite 108 is ±3,611 SF, and Suite 110 is ±21,423 SF.

Property Type:

Flex

Date on Market:

2021-11-19

San Jose Office for Lease - North San Jose

Conference centers & workout centers with showers. On-site management and security. Free parking (surface & secured garages). Close to amenities. Cross Street: Guadalupe Pkwy

Date on Market:

2026-02-06

San Diego Flex for Lease - Sorrento Mesa

Centerpark Labs is a vibrant new development and refreshed life sciences hub in the heart of San Diego’s Sorrento Mesa submarket. An entirely new type of workspace, Centerpark is all about connections. Its integrated design seamlessly connects the indoors to the outdoors, its open spaces bring tenants together, and its generous amenities blur the line between work and “real life.” The dynamic, naturally enhanced campus uplifts the surrounding R&D industrial neighborhood as a beacon of innovation, a place where companies and their employees can thrive, an inviting space to generate community and foster San Diego’s most cutting edge ideas and sciences.

Date on Market:

2025-11-12

Suisun City Office for Lease - Fairfield/Suisun City

Beautiful, Full Service & Affordable Office Space Available. Sunset Plaza has become a favorite amongst all types of business professionals, including startup incubators using it as a springboard for early-stage businesses and startups that want to grow and innovate! We are also starting to see a lot of really cool non-profit groups becoming a success and moving to larger spaces within Sunset Plaza! The affordable, full service office space available at Sunset Plaza has NO extra or hidden fees after the $/Square Foot base rent amount has been agreed to between the landlord and the tenant.) Contact The Elite Club at Vintage Sotheby’s International Realty - Commercial Division to learn more at 707-410-5399 The natural light and friendly atmosphere is a hit amongst tenants, including a very cool property manager that cares about finding the perfect fit for each tenant. Everyone is friendly and says hi! Sunset Plaza is open for business in Suisun / Fairfield. Executive Suites & Flexible Office Space available at 333 Sunset, a gorgeous paean to a now-rare high quality of commercial construction and design. Luxe details provide an inspiring climate for clients, customers, and employees alike. The sense of arrival is palpable, with beautiful landscaping, imposing artist-commissioned sculptures, and strong pillared entry, evoking the Golden Age of Business. This professional 74,537 +/- sq. ft. office bldg. offers 3 stories drenched in fabulous natural light, with invigorating views from nearly every window, perfect for positive productivity and happy employees. Three elevators take you straight to the top, or back down to street level, where you’ll have plenty of room to roam, take in some birdsong, and enjoy the dappled sunlight through mature trees on the 4.03 acre parcel. Ample parking ensures stress-free arrival. 333 Sunset Plaza is a crowning jewel at a bustling intersection of commerce. Cross the street to explore 2 shopping plazas, with Starbucks, shops, restaurants (Thai, BBQ, Chinese, donuts, you name it), health club, bank, post office, local-favorite Raley’s Supermarket, and more! Treat clients to lunch at the charming Suisun Waterfront and Marina, or for a glass of wine at Caymus in the breathtaking vineyards of Suisun Valley. Suisun City is a hub, at the mouth of the Bay and the Delta, with spokes in every direction, to San Francisco, Sacramento, Stockton/Modesto, Napa, and beyond. The capitol Corridor commuter train stops just one exit away for easy commuting. Even Los Angeles is a straight drive from Highway 12 to Highway 5.333 Sunset is full service, with 24 hour security and access, HVAC, and High Speed Internet Service (Comcast and AT&T Available.) Each office space layout is unique, and the landlord is flexible on most floor plans. Love the existing vibe? Most desks, office cubicles, office furniture and partitions are available free of charge to utilize for your office space. With so many amenities, your favorite might just be the value you’ll find for your bottom line! Keep your capital expenditure low, and your balance sheet trim. Bring your business vision to fruition, and lease space at 333 Sunset Avenue in Suisun City / Fairfield.Because, Success is in the Details! Contact us today to learn more and to set up a tour. Also ask about which suites have move in specials! Fun Fact: What is a Full Service Lease? A full-service lease is typically defined as a lease that has one, all-inclusive rental rate which includes both the base lease rate and the operating expenses (property taxes, insurance and common area maintenance) combined into one figure. (Sunset Plaza has NO extra or hidden fees after a $ amount per square foot has been agreed to by the landlord and the tenant.) Disclaimer: Dollar $ per Square foot is subject to change depending on negotiations with the landlord and which space and what if any TI work). Tenants should conduct a careful, independent investigation of the space in person to determine to your satisfaction the suitability of the space for your needs, including all measurements and calculation of area. Information is obtained from various sources and has not been, and will not be, verified by broker or brokers agents. All information about spaces available should be independently reviewed and verified for accuracy by tenant.

Date on Market:

2023-11-08

Irvine Office for Lease - Irvine/Tustin Legacy

Build to Spec to tenant needs. Can be open concept or have multiple private offices. Landlord is easy to work with to help build your Spec Suite to your needs. EASY TO TOUR! On-Site Property Manager available to TOUR M-F 9AM-5PM by Apt Call/Text 209.480-7802

Date on Market:

2025-11-04

Camarillo Office for Lease - Camarillo/Point Mugu

This property at 3601 Calle Tecate in Camarillo, CA is an R&D flex building totaling over 100,000 square feet. It features high ceilings with natural light and offers convenient access to the 101 Freeway. The building underwent its most recent renovations three years ago. Ample parking is available on-site for occupants and visitors.

Property Type:

Flex

Date on Market:

2024-04-03

Morgan Hill Industrial for Lease

Master planned business park Five freestanding state-of-the- art industrial buildings Suitable for advanced manufacturing, life science, industrial and warehouse uses Prominent entry features and extensive window lines Build to suit office space EV charging stations throughout the project

Date on Market:

2021-07-21

San Jose Flex for Lease - North San Jose

Date on Market:

2025-05-20

Upland Flex, Industrial for Lease - Upland/Montclair

Mountain View Industrial Park, located at 1525–1531 W. 13th Street in Upland, California (near the corner of Benson Avenue and 13th Street), offers office, warehouse, commercial, and industrial spaces for lease ranging from 1,445 to 5,752 square feet. This quality business park is set in a secure Upland location and features newer concrete tilt-up buildings, mature landscaping, and excellent curb appeal. Tenants benefit from ample parking for all units, plus additional parking, and easy access to major freeways including the 10, 210, 30, 57, 60, 15, and 71. Each suite provides individual tenant signage, offices equipped with air conditioning, and warehouses with skylights and restrooms. Large ground-level loading doors and 14'–16' minimum ceiling clearance heights support a variety of business operations. Power is robust, with a minimum of 100 Amp, 120/208 Volt, 3-phase service. Permitted uses include office, research and development, distribution, light manufacturing, wholesale, storage, and many other business types. The property also offers DSL/internet technology, professional management, and is located near Cable Airport for added convenience.

Date on Market:

2026-02-19

Thousand Oaks Office for Lease - Thousand Oaks/SE County

Date on Market:

2026-02-02

Beverly Hills Medical for Lease

Prominent Beverly Hills medical office building with exceptional street presence and curated ground-floor dining. The property offers beautifully appointed medical suites with quality existing build-outs as well as build-to-suit opportunities for specialized healthcare users. Ideal for surgical centers, orthopedics, internal medicine, cardiology, plastic and reconstructive surgery, dermatology, ophthalmology, fertility, women’s health, aesthetic medicine, concierge and advanced healthcare practices seeking a premier address. Approximately 380 on-site parking spaces provide an exceptional parking ratio of roughly 5 spaces per 1,000 SF — a rare advantage in Beverly Hills that enhances patient access and operational efficiency. Strategically located near Wilshire Boulevard with convenient access to major corridors, public transportation, and walkable dining, café, and retail amenities.

Property Type:

Office

Date on Market:

2026-03-03

Greenbrae Office/Medical for Lease - San Rafael/Larkspur

Property Type:

Office

Date on Market:

2023-06-28

San Diego Office for Lease - Sorrento Mesa

This three-story, 103,325 SF building was originally built in 1986 and renovated in 2019. The property features an atrium courtyard, monument signage, I-5 & I-805 freeway access, and on-site showers. The property can accommodate a range of different uses including traditional office, light lab and medical. The property is in the Sorrento Mesa submarket and is located adjacent to the new 3RootsSD housing development which has 1,800 homes over 40 acres including 8 miles of trails as well as upcoming restaurants. Please let us know if you would like to tour!

Date on Market:

2026-02-24

Chatsworth Industrial for Lease - Western SFV

THINK SPACE REAL ESTATE, INC is pleased to present the opportunity to lease this State-of-the-Art Industrial / R & D Facility / Flex / Lab Space / Showroom in Prime Chatsworth Location. Property is located in STATE ENTERPRISE ZONE, EMPLOYMENT AND ECONOMIC INCENTIVE PROGRAM AREA (EZ), an area where businesses can take advantage of State Tax Credits and deductions not available to businesses elsewhere. These incentives include hiring, tax credits, sales, use tax credits, and electricity rate subsidies. In addition, property has also been situated in Chatsworth-Northridge Industrial Core, called "INNOV818". The San Fernando Valley is historically the technological core of the aerospace industry in southern California. The West Valley has been the hub of industry and innovation going back to the beginnings of the aerospace industry. In fact, in the early 1960’s, 70% of the Valley’s 1 million residents depended on this industry for their livelihood. As a result, the Chatsworth and Northridge communities are home to many restricted light industrial properties which need to be preserved, in as much as the zones and accompanying land use categories are suitable for the location of high tech, clean-tech, green-tech and bio-tech uses. This area is unique in the City of Los Angeles as one of the few contiguous areas with this tremendous opportunity for multiple complimentary uses. Moreover, property is also located in the OPPORTUNITY ZONE. Please check with the Listing Broker regarding the use. Please contact the Broker for additional information. NNN/CAM charges are currently estimated at about $0.28/SF/month. Please do not disturb the current occupants, showings and tours are by appointment only. Please verify square footage and zoning for intended use. ALL INFORMATION DEEMED RELIABLE BUT NOT GUARANTEED

Date on Market:

2025-02-25

San Diego Office/Medical for Lease - Sorrento Valley

Property Type:

Flex

Date on Market:

2026-02-04

Los Angeles Medical for Lease - Koreatown

» Five-story, 147,078 SF Class A medical office building » Centrally located in downtown Los Angeles adjacent to St. Vincent Medical Center » 1.3 miles from the 110 Freeway and 0.5 miles from Westlake/MacArther Park subway station » Six hospitals within 8 miles including Good Samaritan Hospital (1.0 mile), California Hospital Medical Center (2.8 miles), White Memorial Medical Center (4.0 miles), LA & USC Medical Center (4.6 miles), and Community Hospital of Huntington (8.2 miles) » Building features the largest concentration of high-grade laboratory space in the Downtown Los Angeles submarket » Tenants include AltaMed Health Services Corporation, Children’s Hospital of Los Angeles, Providence Health & Services, Viracor-IBT and UCLA Health

Property Type:

Office

Date on Market:

2024-08-08

Scotts Valley Office, Retail for Lease

Welcome to 230 Mt Hermon Rd, a dynamic commercial opportunity located in the bustling King's Village Shopping Center of Scotts Valley, CA. This versatile property offers a mix of retail and office spaces ideal for businesses seeking visibility and convenience. Tenants benefit from full buildouts, flexible lease terms, and proximity to high-traffic anchor stores like Nob Hill Foods, Walgreens, and CineLux Theatres. The center boasts 120 surface parking spaces, excellent walkability, and a vibrant tenant mix that draws consistent foot traffic. Whether you're launching a boutique, expanding a professional office, or establishing a lab or wellness space, this location provides the infrastructure and community to thrive.

Date on Market:

2025-12-11

Irvine Office for Lease - Irvine Spectrum

You are the revolutionary working to discover the next breakthrough, wanting to change the present and better the future. Cultivate your next big idea in your exclusive workspace and access the benefits of the larger ecosystem within Discovery Park. Discover your company's next gen.

Date on Market:

2026-02-19

Campbell Office, Office/Medical for Lease

Maximum contiguous 40,000 S. F. Great West Valley location. Near junction of 17 & 85. Not far from 280 and 101. Cross section Camden road in Silicon Valley. Walking distance to all amenities. Flexible Lease terms. Zoning and General Plan M1 (Light Industrial), Flexible Zoning that has Abundant Permitted and Conditional Uses. Office. Medical. Medical device company. Biotech. Clean room. R&D. Laboratory Lab space. Multiple clean rooms. Lots of power! Surgical center. Ambulatory surgery site. Animal surgical. Animal Hospital. Veterinary Care. Imaging center. Ortho Rehab center. Speciality center. High ceilings. Roll up doors. Shipping & Handling. Veterinary clinic. Veterinary hospital. Sports and Fitness use. Animal day care. Office General Industrial. Visible from highway 17. Signage for major tenant.

Date on Market:

2022-08-16

Menlo Park Flex for Lease - Redwood City

Premier laboratory and flex space designed for research and development at Edison Technology Park, Menlo Park. Edison Technology Park features 22-foot-high ceilings, skylights, yard space, an en-suite kitchenette, drive-in bays, an innovative solar facade, and 100/400-amp, 3-phase power supply. On-site amenities include parking with charging stations, signage opportunities, and a solar generation plant that powers all businesses within the park. Edison Technology Park offers flexible zoning allowing for a variety of uses. This is an ideal space for any tenant looking to thrive in a dynamic environment and add to the synergy of an established technology park. In the heart of Menlo Park, Edison Technology Park offers exceptional access to major thoroughfares, including Highway 101, Interstate 280, Woodside Road, and El Camino Real, making commuting and logistics. Menlo Park, known for its proximity to Silicon Valley, is less than 3 miles away, providing tenants access to one of the world’s most innovative tech hubs. The area also boasts convenient transportation options, including access to the Atherton CalTrain Station and nearby bus stops along El Camino Real. Tenants will benefit from being close to national retailers such as Target, Marshalls, and Costco, as well as local dining spots like Dickey’s Barbecue Pit and Brew Coffee and Bakery. The Menlo Park area offers an appealing mix of commercial and residential appeal. The surrounding neighborhood is home to over 260,000 residents within a 5-mile radius, with nearly 60% of the population holding a bachelor's degree or higher, providing businesses with access to a well-educated workforce. With its central location, businesses can easily tap into the dynamic talent pool of Silicon Valley, and the convenience of three international airports within a 17- to 28-mile radius, San Francisco, San Jose, and Oakland Airports, ensures global connectivity. With its flexible zoning, infrastructure, and proximity to essential amenities, this prime location, creates a highly attractive environment for any business looking to grow and innovate.

Date on Market:

2025-06-06

Santa Ana Retail for Lease - Civic Center Area

515 N Sycamore Street offers a prime leasing opportunity in the heart of Santa Ana, just steps from the vibrant Downtown district and across from the historic Old Orange County Courthouse. This six-story office building spans approximately 41,864 square feet and provides a mix of office and retail spaces designed for professional services and boutique businesses. The property’s central location ensures excellent walkability, with easy access to local eateries, retail shops, and cultural attractions, making it an ideal setting for businesses seeking visibility and convenience. The building features controlled access, 24-hour availability, fiber optic internet, and on-site property management, ensuring a secure and efficient work environment. Tenants benefit from both surface and covered parking options, supporting accessibility for employees and clients. With its proximity to Santa Ana Boulevard and major transportation routes, including nearby Metrolink stations, this property offers outstanding connectivity throughout Orange County. Positioned in a dynamic urban setting with strong demographics and a thriving business community, 515 N Sycamore Street is an excellent choice for companies looking to establish or expand their presence in Santa Ana.

Property Type:

Office

Date on Market:

2022-02-02

Huntington Beach Office/Medical for Lease

Renovated Medical and dental office building in downtown Medical District in Huntington Beach. It is a two-story beautiful garden style building which has total 23,271sf on one acre land which provides abundant free parking that is rare in downtown Huntington Beach. Next Building also has a huge parking lot on 2-acre land. All office suites are in an excellent move in condition. Available spaces are from 1187 sf to 1187 sf. All office suites have one or two in-suite bathrooms. Additional disability accessible bathroom is also available in the building. All suites have its own HVAC. Tenants can adjust the temperature to their comfort. All suites have windows which can be opened to get fresh ocean breeze. There are seating areas in courtyard and Hallways for tenants and patients to enjoy fresh ocean breeze which is very good for human health. Newly re-modernized elevator for second story tenants and patients to use. Beautiful water fountain in the courtyard. Current Tenants including Diabetes Clinic, Periodontics Clinic, General Dental Clinic, Foot and Ankle Surgeon Clinic, Dermatologist Clinic, Medical Sports rehabilitation, Medical Laser and Aesthetics, Acupuncture Clinics, Chiropractic Clinics, Women's Health and Wellbeing. The building has Newer low E double pane windows, many of them can be opened to have fresh ocean breeze enter into offices for a healthy working environment. It is in a few minutes walking distance to 5 Point senior living, 5-point plaza and many other shopping centers, Trader' Joe's, restaurants in Downtown area. 2 miles to Huntington Beach Pier, 1.3 Miles to Huntington Beach hospital, 3 miles to Orange Coast Memorial Hospital. The building renovation was done in 2020 to 2021, including new roof, new windows, new colored paint, beautification of the landscape, Re-modernized elevator, signage tower, plumbing and electricals. Please call or text Gexin Tang at 949 836 1888 or email : Tanggexin@yahoo.com for any questions or showing appointment.

Property Type:

Office

Date on Market:

2026-03-05

Los Gatos Flex for Lease - Los Gatos/Saratoga

Date on Market:

2025-11-12